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Soft Tissue Sarcoma

Your soft tissues connect, support or surround other tissues. Examples include your muscles, tendons, fat and blood vessels. Soft tissue sarcoma is a cancer of these soft tissues. There are many kinds, based on the type of tissue they started in. Sometimes they spread and can press on nerves and organs, causing problems such as pain or trouble breathing.

No one knows exactly what causes these cancers. They are not common, but you have a higher risk if you have been exposed to certain chemicals, had radiation therapy or have certain genetic diseases.

To diagnose soft tissue sarcomas, doctors must remove and look at a piece of the tumor under a microscope. Treatments include surgery to remove the tumor, radiation therapy, chemotherapy or a combination

Ewing sarcoma

Ewing sarcoma is the second most common tumor of the bone. It most often affects bones of the pelvis, the tibia, fibula, and femur, and can also begin in the soft tissues. This disease most often occurs in adolescents, with nearly half of cases arising between the ages of 10 and 20.

What are the prognostic factors in Ewing sarcoma?

The extent of the disease is the most important factor in determining how the disease will progress. Other factors that influence the prognosis include: -
  • Primary site (where the cancer began)
  • The presence of metastasis (spreading to other areas)
  • Size of the tumor
  • Age
  • Leukocyte count
  • Sedimentation rate
  • Serum LDH levels

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